An engineered enzyme offers substantial efficiency advantages in the production-scale synthesis of a drug.Authors: Christopher K. Savile, Jacob M. Janey, Emily C. Mundorff, Jeffrey C. Moore, Sarena Tam, William R. Jarvis, Jeffrey C. Colbeck, Anke Krebber, Fred J. Fleitz, Jos Brands, Paul N. Devine, Gjalt W. Huisman, Gregory J. Hughes